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Antigenic Specificity | E2F6 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: E2F6 antibody detects endogenous levels of total E2F6. E2F6 Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. |
Immunogen | Immunogen: A synthesized peptide derived from human E2F6 |
Other Names | [E2F transcription factor 6; E2F transcription factor 6; isoform 1; E2F-6; E2F6; MGC111545; Transcription factor E2F6] |
Gene, Accession # | [E2F6], Gene ID: 1876, NCBI: NP_001265204.1, UniProt: O75461 |
Catalog # | MBS8510647 |
Price | $290 |
Order / More Info | E2F6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |