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Antigenic Specificity | Human IL-21 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA), Neutralization (N) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include: inducing the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells; the stimulation of IgG production in conjunction with IL-4; and the induction of apoptotic effects in nai?ve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the gamma chain found in other cytokine receptors, including IL-2, IL-4, IL-7 |
Immunogen | n/a |
Other Names | [Interleukin-21; Za11], [IL21; IL21; Za11; IL-21; CVID11; IL-21] |
Gene, Accession # | [IL-21], Gene ID: 59067, NCBI: NP_001193935.1, UniProt: Q9HBE4 |
Catalog # | MBS692503 |
Price | $415 |
Order / More Info | Human IL-21 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |