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Antigenic Specificity | Nestin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Protein Mdm4(MDM4) detection. Tested with WB, IHC-P in Human;Rat. Background: Nestin is a type VI intermediate filament (IF) protein that in humans is encoded by the NES gene. This gene is mapped to 1q23.1. Distribution and expression of nestin in mitotically active cells suggests it plays a role in regulation of the assembly and disassembly of intermediate filaments, which, together with other structural proteins, participate in remodeling of the cell. The role of nestin in dynamic cells, particularly structural organization of the cell, appears strictly regulated by phosphorylation, especially its integration into heterogeneous intermediate filaments together with vimentin or alpha-internexi |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Nestin (252-290aa ERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAH), different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids. Ig Type: Rabbit IgG |
Other Names | [Nestin; ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; nes; NEST_HUMAN; Nestin; nestin], [NES; NES; Nbla00170] |
Gene, Accession # | Gene ID: 10763, NCBI: NP_006608.1, UniProt: P48681 |
Catalog # | MBS178078 |
Price | $315 |
Order / More Info | Nestin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Guerette D, Khan PA, Savard PE, Vincent M (2007). Molecular evolution of type VI intermediate filament proteins. BMC Evol. Biol. 7: 164. 2. Michalczyk K, Ziman M (April 2005). Nestin structure and predicted function in cellular cytoskeletal organisation. Histol. Histopathol. 20 (2): 665-71. |