Nestin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNestin
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Protein Mdm4(MDM4) detection. Tested with WB, IHC-P in Human;Rat. Background: Nestin is a type VI intermediate filament (IF) protein that in humans is encoded by the NES gene. This gene is mapped to 1q23.1. Distribution and expression of nestin in mitotically active cells suggests it plays a role in regulation of the assembly and disassembly of intermediate filaments, which, together with other structural proteins, participate in remodeling of the cell. The role of nestin in dynamic cells, particularly structural organization of the cell, appears strictly regulated by phosphorylation, especially its integration into heterogeneous intermediate filaments together with vimentin or alpha-internexi
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Nestin (252-290aa ERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAH), different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids. Ig Type: Rabbit IgG
Other Names[Nestin; ESTM 46; FLJ 21841; FLJ21841; Intermediate filament protein; Nbla00170; nes; NEST_HUMAN; Nestin; nestin], [NES; NES; Nbla00170]
Gene, Accession #Gene ID: 10763, NCBI: NP_006608.1, UniProt: P48681
Catalog #MBS178078
Price$315
Order / More InfoNestin Antibody from MYBIOSOURCE INC.
Product Specific References1. Guerette D, Khan PA, Savard PE, Vincent M (2007). Molecular evolution of type VI intermediate filament proteins. BMC Evol. Biol. 7: 164. 2. Michalczyk K, Ziman M (April 2005). Nestin structure and predicted function in cellular cytoskeletal organisation. Histol. Histopathol. 20 (2): 665-71.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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