ATG4C Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ATG4C |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total ATG4C protein. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation By similarity. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.Marino G., J. Biol. Chem. 278:3671-3678(2003).Ch |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human ATG4C. |
| Other Names | [APG4 autophagy 4 homolog C; APG4-C; APG4C; AUT-like 3 cysteine endopeptidase; AUTL1] |
| Gene, Accession # | [ATG4C], Gene ID: 84938, NCBI: NP_116241.2, UniProt: Q96DT6 |
| Catalog # | MBS9405139 |
| Price | $200, $255 |
| Order / More Info | ATG4C Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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