IFN-gamma Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIFN-gamma
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein A purified
Size0.1 mg
Concentration1ug/ul
ApplicationsELISA (EIA), Western Blot (WB)
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Descriptioninterferon-gamma (IFN-gamma) is a pro-inflammatory cytokine that is central in host resistance to infection. It is mainly produced by natural killer cells and CD4+ and CD8+ T cells, its receptors are found on nearly all cells, where it activates diverse responses that enable potential host cells to prevent invasive infection by bacteria, parasites and viruses. Takayanagi et al. (2000) demonstrated that IFN-? strongly suppresses osteoclastogenesis by interfering with the RANKL (602642)-RANK (603499) signaling pathway. Tsubota et al. (1999) reported that this upregulation in Sjogren syndrome patients may be controlled by interferon-gamma through the activation of transcription factor NFKB.
ImmunogenImmunogen: Ni-NTA purified recombinant human IFN-gamma expressed in E Coli strain BL21 (DE3)
Other Names[interferon gamma; Interferon gamma; interferon gamma; interferon gamma; Immune interferon], [IFNG; IFNG; IFG; IFI; IFN-gamma]
Gene, Accession #[IFN-gamma], Gene ID: 3458, NCBI: NP_000610.2, UniProt: P01579
Catalog #MBS418391
Price$445
Order / More InfoIFN-gamma Antibody from MYBIOSOURCE INC.
Product Specific References1. Takayanagi, H. et al. Nature 2000. 408: 600-605. 2. Tsubota, K. et al. Invest. Ophthal. Vis. Sci. 40: 28-34, 1999.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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