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Antigenic Specificity | RNF34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen | Immunogen: Recombinant protein of human RNF34 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CARP-1; CARP1; RFI; RIF; RIFF; hRFI] |
Gene, Accession # | [RNF34], Gene ID: 80196, NCBI: NP_001243787.1, UniProt: Q969K3 |
Catalog # | MBS8536777 |
Price | $300 |
Order / More Info | RNF34 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |