Complement 3d (C3d) (Acute Humoral Rejection Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Complement 3d (C3d) (Acute Humoral Rejection Marker) |
| Clone | [C3D/2891] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The complement component proteins, C2, C3, C4 and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to their respective G protein-coupled receptors, C3aR, C1R and C5aR, induces proinflammatory events, such as cellular degranulation, smooth muscle contraction, arachidonic acid metabolism, cytokine release, leukocyte activation and cellular chemotaxis. C3d is a terminal degradation product of C3 that plays an important role in modulation of the adaptive immune response through the interaction with complement receptor type 2 (CR2). CR2 is important in the switched-isotype, high-affinity and memory humoral immune responses to T-dependent foreign antigens, as well as in the development of the |
| Immunogen | Immunogen: Recombinant full-length human Complement C3 protein |
| Other Names | [Acylation stimulating protein cleavage product; AHUS5; ARMD9; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement component C3; CPAMD1] |
| Gene, Accession # | [C3d], Gene ID: 718, NCBI: AAI50180.1, UniProt: P01024 |
| Catalog # | MBS4381315 |
| Price | $190, $340, $340 |
| Order / More Info | Complement 3d (C3d) (Acute Humoral Rejection Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nagar, B., et al. 1998. X-ray crystal structure of C3d: a C3 fragment and ligand for CR2. Science 280: 1277-1281. 2. Clemenza, L., et al. 2000. Structure-guided identification of C3d residues essential for its binding to CR2 (CD21). J. Immunol. 165: 3839-3848 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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