Amyloid-beta (N-term), Human Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAmyloid-beta (N-term), Human
CloneVU17
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Formalin/Paraffin, Immuno Assay (IA), Immunoprecipitation (IP)
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DescriptionAntibody clone VU17, formerly known as alphaVU Abeta 17, recognizes the N-terminus of human amyloid beta (i.e. in: Abeta1-38; Abeta1-39; Abeta1-40; Abeta1-42). Amyloid beta peptides are of key importance in the development of Alzheimer's disease (AD) and are present in CSF. AD affects approximately 1% of the population over the age of 80. The disease is characterized by aggregation of Abeta into oligomers, fibrils and plaques deposition of insoluble and aggregated protein in the brain where its neurotoxic action leads to neuronal cell death. The deposits, also called amyloid plaques, are formed around the neuropil. The exact molecular mechanism is still unclear. Abeta is a proteolytic cleavage product, by APP-cleaving enzyme 1 (BACE1) and b
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS584771
Price$520
Order / More InfoAmyloid-beta (N-term), Human Antibody from MYBIOSOURCE INC.
Product Specific References1. Verwey, N et al; Immunohistochemical characterization of novel monoclonal antibodies against the N-terminus of amyloid beta-peptide. Amyloid 2013, 20:3 2. Verwey, N et al; Quantification of amyloid beta 40 in cerebrospinal fluid. Journal of Immunology methods 2009, 348:1-2
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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