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Antigenic Specificity | Mouse KLRG1 |
Clone | monoclonal |
Host Species | Syrian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: KLRG1 (Mr 30-38 kDa). The monoclonal antibody 2F1 reacts with mouse killer cell lectin-like receptor G1 (KLRG1; formerly known as mouse MAFA or 2F1-Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. The 2F1 antibody stains 30-60% of NK1.1+CD3-splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors. |
Immunogen | Immunogen: Activated NK (A-LAK) cells from B6 (H-2b) mice Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide. |
Other Names | [killer cell lectin-like receptor subfamily G member 1 isoform b; Killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin like receptor G1; C-type lectin domain family 15 member A; ITIM-containing receptor MAFA-L; MAFA-like receptor; Mast cell function-associated antigen] |
Gene, Accession # | [KLRG1], Gene ID: 10219, NCBI: NP_005801.3, UniProt: Q96E93 |
Catalog # | MBS4151894 |
Price | $445 |
Order / More Info | Mouse KLRG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |