Mouse KLRG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse KLRG1
Clonemonoclonal
Host SpeciesSyrian Hamster
Reactive Speciesmouse
IsotypeIgG
Formataffinity purified
Size0.1 mg
Concentration100ug/200ul
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionSpecificity: KLRG1 (Mr 30-38 kDa). The monoclonal antibody 2F1 reacts with mouse killer cell lectin-like receptor G1 (KLRG1; formerly known as mouse MAFA or 2F1-Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. The 2F1 antibody stains 30-60% of NK1.1+CD3-splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors.
ImmunogenImmunogen: Activated NK (A-LAK) cells from B6 (H-2b) mice Storage Buffer: PBS, pH 7.4 with 0.05% sodium azide.
Other Names[killer cell lectin-like receptor subfamily G member 1 isoform b; Killer cell lectin-like receptor subfamily G member 1; killer cell lectin-like receptor subfamily G member 1; killer cell lectin like receptor G1; C-type lectin domain family 15 member A; ITIM-containing receptor MAFA-L; MAFA-like receptor; Mast cell function-associated antigen]
Gene, Accession #[KLRG1], Gene ID: 10219, NCBI: NP_005801.3, UniProt: Q96E93
Catalog #MBS4151894
Price$445
Order / More InfoMouse KLRG1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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