DTNBP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDTNBP1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionComponent of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton re
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human DTNBP1 (NP 115498.2).
Other Names[SDY; DBND; HPS7; My031; BLOC1S8]
Gene, Accession #[DTNBP1], Gene ID: 84062, NCBI: Q96EV8.1, UniProt: Q96EV8
Catalog #MBS8544496
Price$280
Order / More InfoDTNBP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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