COPS5 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | COPS5 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This COPS5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-222 amino acids from the Central region of human COPS5. Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosph |
| Immunogen | n/a |
| Other Names | [Purified Rabbit (Pab); COP9 signalosome complex subunit 5; SGN5; Signalosome subunit 5, 34--; Jun activation domain-binding protein 1; COPS5; CSN5; JAB1] |
| Gene, Accession # | [COPS5], Gene ID: 10987, NCBI: NP_006828.2, UniProt: Q92905 |
| Catalog # | MBS9216316 |
| Price | $165, $370 |
| Order / More Info | COPS5 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Claret F.-X.,et al.Nature 383:453-457(1996). Asano K.,et al.J. Biol. Chem. 272:27042-27052(1997). Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Bienvenut W.V.,et al.Submitted (OCT-2005) to UniProtKB. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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