PABPC1 (Center), 250-279 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPABPC1 (Center), 250-279
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (predicted reactivity: bovine, rat, Xenopus)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1. PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD
Immunogenn/a
Other Names[Polyadenylate-binding protein 1; PABP-1; Poly(A)-binding protein 1; PABPC1; PAB1; PABP1; PABPC2]
Gene, Accession #[PABPC1], Gene ID: 26986, NCBI: NP_002559.2, UniProt: P11940
Catalog #MBS9204504
Price$165, $370
Order / More InfoPABPC1 (Center), 250-279 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLe Clerc,S., et.al., J. Infect. Dis. 200 (8), 1194-1201 (2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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