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Antigenic Specificity | PABPC1 (Center), 250-279 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine, rat, Xenopus) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1. PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD |
Immunogen | n/a |
Other Names | [Polyadenylate-binding protein 1; PABP-1; Poly(A)-binding protein 1; PABPC1; PAB1; PABP1; PABPC2] |
Gene, Accession # | [PABPC1], Gene ID: 26986, NCBI: NP_002559.2, UniProt: P11940 |
Catalog # | MBS9204504 |
Price | $165, $370 |
Order / More Info | PABPC1 (Center), 250-279 Antibody from MYBIOSOURCE INC. |
Product Specific References | Le Clerc,S., et.al., J. Infect. Dis. 200 (8), 1194-1201 (2009) |