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Antigenic Specificity | Mouse CD98 |
Clone | [H202-529.4.1.4] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.25 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CD98 antibody, clone H202-529.4.1.4 recognizes murine CD98, also known as 4F2 and SLC3A2. CD98 is a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex. CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important rol |
Immunogen | Immunogen: Thymic epithelial cells from mouse Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [4F2 cell-surface antigen heavy chain isoform a; 4F2 cell-surface antigen heavy chain; 4F2 cell-surface antigen heavy chain; CD98 antigen; CD98 heavy chain; antigen identified by 4F2; solute carrier family 3 member 2; type II transmembrane protein; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; Solute carrier family 3 member 2; CD_antigen: CD98], [Slc3a2; Slc3a2; 4F2; Cd98; Ly10; Mdu1; 4F2HC; Ly-10; NACAE; Ly-m10; Mgp-2hc; AI314110; Mdu1; 4F2hc] |
Gene, Accession # | [CD98], Gene ID: 17254, NCBI: NP_001154885.1, UniProt: P10852 |
Catalog # | MBS217360 |
Price | $430 |
Order / More Info | Mouse CD98 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |