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Antigenic Specificity | IGF2R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2327-2491 of human IGF2R (NP 000867.2). |
Other Names | [MPR1; MPRI; CD222; CIMPR; M6P-R; MPR300; CI-M6PR; MPR 300; M6P/IGF2R] |
Gene, Accession # | [IGF2R], Gene ID: 3482, NCBI: NP_000867.2, UniProt: P11717 |
Catalog # | MBS8548786 |
Price | $280 |
Order / More Info | IGF2R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |