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Antigenic Specificity | Mouse CD70: RPE |
Clone | [FR70] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | phycoerythrin (RPE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CD70 antibody, clone FR70 recognizes mouse CD70, a 30-33 kDa type II transmembrane protein belonging to the TNF superfamily. CD70 is not expressed on resting T cells and B cells but expression is induced on activation. Interaction of CD70 with its ligand CD27 is reported to play an important role in T cell co-stimulation and the regulation of T-dependant B cell activation and antibody production. Clone FR70 is reported to block the functions of CD70 and has been used to block the interactions between CD27 and CD70 (Oshima et al.). |
Immunogen | Immunogen: A20 mouse B cell lymphoma cell line. Conjugation: RPE |
Other Names | [CD70 (FR70)], [Cd70; Cd70; Cd27l; CD27LG; Tnfsf7; Tnlg8a; Cd27l; Cd27lg; Tnfsf7; CD27-L] |
Gene, Accession # | [CD70], Gene ID: 21948, NCBI: O55237.1, UniProt: O55237 |
Catalog # | MBS225654 |
Price | $450 |
Order / More Info | Mouse CD70: RPE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |