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Antigenic Specificity | CYP1A1 (Center), 252-280 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CYP1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-280 amino acids from the Central region of human CYP1A1. CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 gene has been associated with lung cancer risk. |
Immunogen | n/a |
Other Names | [Cytochrome P450 1A1; CYPIA1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; CYP1A1] |
Gene, Accession # | [CYP1A1], Gene ID: 1543, NCBI: NP_000490.1, UniProt: P04798 |
Catalog # | MBS9207855 |
Price | $165, $370 |
Order / More Info | CYP1A1 (Center), 252-280 Antibody from MYBIOSOURCE INC. |
Product Specific References | Delpisheh,A., Eur. J. Obstet. Gynecol. Reprod. Biol. 143 (1), 38-42 (2009) Zhuo,W., Cancer Invest. 27 (1), 86-95 (2009) |