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Antigenic Specificity | CD58 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect CD58 in human, mouse and rat samples. Background: CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of its cognate ligand, CD2, on the T cell s |
Immunogen | Immunogen: This CD58 antibody is generated from KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD58. The exact sequence is proprietary. Positive Control: WB: HEK293T, Raw264.7, H9C2 whole cell lysates |
Other Names | [LFA3; Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; CD58], [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3] |
Gene, Accession # | [CD58], Gene ID: 965, NCBI: NP_001138294.1, UniProt: P19256 |
Catalog # | MBS840454 |
Price | $240 |
Order / More Info | CD58 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |