Phospho-Histone H3 (Ser57) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Histone H3 (Ser57) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, ratpredicted: bovine |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-Histone H3 (Ser57) Antibody detects endogenous levels of Histone H3 only when phosphorylated at Ser57. Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Post Translational Modifications: Acetylation is generally linked to gene activation. Acetylation on Lys-10 (H3K9ac) impairs methylation at Arg-9 (H3R8me2s). Acetylati |
| Immunogen | Immunogen: A synthesized peptide derived from human Histone H3 around the phosphorylation site of Ser57. Tissue Specificity: Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. |
| Other Names | [H3 histone family, member A; H3/A; H31_HUMAN; H3FA; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1, H3a; Histone cluster 1, H3a; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l] |
| Gene, Accession # | NCBI: NP_003520.1, UniProt: P68431 |
| Catalog # | MBS9610697 |
| Price | $225, $280, $340 |
| Order / More Info | Phospho-Histone H3 (Ser57) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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