DR4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDR4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionBackground: Apoptosis can be induced by certain cytokines including TNF and Fas Ligand of the TNF super-family thromugh their death domain (DD) containing receptors, TNFR1 and Fas. A member of the TNF receptor family was recently identified and designated DR4 (death receptor 4) and TRAIL-R1. The ligand for this novel death receptor has been identified and termed TRAIL. DR4 is expressed in most of the human tissues including spleen, peripheral blood leukocytes (PBLs), small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NFkB activation in many tissues and cells.
ImmunogenImmunogen: Synthetic peptide corresponding to residues surrounding amino acids 454 of human DR4
Other Names[TNFRSF10A; TRAILR1; MGC9365; APO2; CD261; TRAIL-R1; TRAILR-1], [TNFRSF10A; TNFRSF10A; DR4; APO2; CD261; TRAILR1; TRAILR-1; APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1]
Gene, Accession #[DR4], Gene ID: 8797, NCBI: NP_003835.3, UniProt: O00220
Catalog #MBS841425
Price$150, $290
Order / More InfoDR4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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