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Antigenic Specificity | Cdk2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 2(CDK2) detection. Tested with WB in Human, Mouse, Rat. Background: CDK2, Cyclin-Dependent Kinase2, is also know as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65% sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk2 (277-298aa AKAALAHPFFQDVTKPVPHLRL), identical to the related rat and mouse sequences. |
Other Names | [Cyclin-dependent kinase 2; cyclin-dependent kinase 2; Cdc2 related protein kinase; cdc2-related protein kinase; Cdk 2; CDK2; CDK2_HUMAN; Cell devision kinase 2; Cell division kinase 2; Cell division protein kinase 2; Cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 2; p33 protein kinase; p33(CDK2)], [CDK2; CDK2; CDKN2; p33(CDK2); CDKN2] |
Gene, Accession # | [CDK2], Gene ID: 1017, NCBI: P24941.2, UniProt: P24941 |
Catalog # | MBS175108 |
Price | $280 |
Order / More Info | Cdk2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |