Edit |   |
---|---|
Antigenic Specificity | PARP1 (2G10) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, monkey, mouse, Chinese hamster, dog, rat |
Isotype | IgG |
Format | unconjugated |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PARP1 monoclonal antibody detects endogenous levels of PARP1 protein. This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, PARP1 may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
Immunogen | Source Note: This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to surface multi-epitopes of human PARP1. |
Other Names | [PARP1, partial; Poly [ADP-ribose] polymerase], [PARP1; PARP] |
Gene, Accession # | [PARP1], NCBI: JAO80662.1 |
Catalog # | MBS435068 |
Price | $350, $565 |
Order / More Info | PARP1 (2G10) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |