MAP2K3 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMAP2K3 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript va
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAP2K3
Other Names[dual specificity mitogen-activated protein kinase kinase 3 isoform A; Dual specificity mitogen-activated protein kinase kinase 3; dual specificity mitogen-activated protein kinase kinase 3; mitogen-activated protein kinase kinase 3; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2]
Gene, Accession #[MAP2K3], Gene ID: 5606, NCBI: NP_001303261.1, UniProt: P46734
Catalog #MBS3222396
Price$335
Order / More InfoMAP2K3 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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