TNFAIP3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFAIP3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorecence (IF)
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DescriptionA20, also referred to as TNF-alpha-induced protein 3 (TNFAIP3), is cytokine-inducible protein that functions to inhibit apoptosis and activate NF-kappaB (1,2). It was first identified as a TNF-alpha inducible primary response gene in human umbilical vein endothelial cells, and encodes a 790-amino acid protein containing seven Cys2/Cys2-zinc finger motifs (3). Constitutive expression of A20 is observed in lymphoid tissues (4), but it is transiently expressed in a variety of cell types in response to inflammatory signals such as TNF-alpha (3,5), IL-1 (3,5), phorbol esters (6), and LPS (7). Expression of A20 can confer resistance to apoptosis and NF-kappaB activation triggered by these signals, probably through interference with TRAF (TNF rece
ImmunogenImmunogen: Recombinant Protein
Other Names[A20; MGC104522; MGC138687; MGC138688; OTUD7C; TNFA1P2], [TNFAIP3; TNFAIP3; A20; OTUD7C; TNFA1P2; OTUD7C; TNF alpha-induced protein 3]
Gene, Accession #[TNFAIP3], Gene ID: 7128, NCBI: P21580.1, UniProt: P21580
Catalog #MBS126517
Price$200, $275, $430
Order / More InfoTNFAIP3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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