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Antigenic Specificity | HIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HIP1 polyclonal antibody. Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway.Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors |
Immunogen | Immunogen: Recombinant Human Huntingtin-interacting protein 1 protein(410-690aa) |
Other Names | [HIP-1; Huntingtin-interacting protein I; HIP-I] |
Gene, Accession # | [HIP1], Gene ID: 3092, NCBI: NP_001230127.1, UniProt: O00291 |
Catalog # | MBS9416270 |
Price | $320 |
Order / More Info | HIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |