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Antigenic Specificity | C14orf169 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.1mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total C14orf169 protein. Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May |
Immunogen | Immunogen: Synthetic peptide of human C14orf169 Immunogen Type: Peptide |
Other Names | [ROX; NO66; MAPJD; URLC2; hsNO66] |
Gene, Accession # | [C14orf169], Gene ID: 79697, NCBI: NP_078920.2, UniProt: Q9H6W3 |
Catalog # | MBS9417286 |
Price | $255 |
Order / More Info | C14orf169 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |