ALK (C-term), 1591-1620 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ALK (C-term), 1591-1620 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 1.43 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1591~1620 amino acids from the C-terminal region of human ALK. ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2;5)(p23;q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains. |
| Immunogen | n/a |
| Other Names | [ALK tyrosine kinase receptor; Anaplastic lymphoma kinase; CD246; ALK] |
| Gene, Accession # | [ALK], Gene ID: 238, NCBI: NP_004295.2, UniProt: Q9UM73 |
| Catalog # | MBS9203898 |
| Price | $165, $370 |
| Order / More Info | ALK (C-term), 1591-1620 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Morris, S.W., et al., Oncogene 14(18):2175-2188 (1997). Iwahara, T., et al., Oncogene 14(4):439-449 (1997). Morris, S.W., et al., Science 263(5151):1281-1284 (1994). Morris, S.W., et al., Oncogene 15, 2883-2883 (1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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