Bcl-10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBcl-10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionBcl-10 Antibody: Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF-κB activation. Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphomas
ImmunogenImmunogen: Bcl10 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human Bcl10. Buffer: Bcl-10 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Bcl-10; CLAP; mE10; CIPER; c-E10; CARMEN; CLAP; CARD-containing molecule enhancing NF-kappa-B; Bcl-10; B-cell CLL/lymphoma 10], [BCL10; BCL10; CLAP; mE10; CIPER; IMD37; c-E10; CARMEN; CIPER; CLAP; Bcl-10; hCLAP; CIPER; cCARMEN; c-E10; mE10]
Gene, Accession #[BCL10], Gene ID: 8915, NCBI: AF134395, UniProt: O95999
Catalog #MBS150410
Price$375
Order / More InfoBcl-10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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