Human Caspase-2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Caspase-2 |
| Clone | [SB123a1] |
| Host Species | Rat |
| Reactive Species | human |
| Isotype | IgM |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Reacts with human Caspase 21. The Caspases are a family of cysteine proteases that induce apoptosis in response to a variety of intraand extracellular stimuli. These enzymes are synthesized as inactive precursors which become cleaved at aspartate-specific sites upon induction of apoptosis. Caspase 2 (ICH-1/Nedd2) is an initiator caspase that is prevalent in both the cytosol and nucleus in many cell types3. During embryonic development it is expressed at relatively high levels in the central nervous system, liver, kidney and lungs and is prevalent in numerous tissues in adults4,5. Studies have shown that Caspase 2 becomes activated in response to several lethal stimuli including DNA damage, ER stress and death receptor stimulation and furthe |
| Immunogen | Immunogen: Purified native human Caspase 2. Characterization: To ensure acceptable performance, each batch of product is tested by ELISA to conform to characteristics of a standard reference reagent. |
| Other Names | [Rat Human Caspase 2], [Casp2; Casp2; ICH-1; Nedd2; Caspase-2; Ich1; Nedd-2; Nedd2; CASP-2; NEDD-2] |
| Gene, Accession # | Gene ID: 12366, NCBI: NP_031636.1, UniProt: P29594 |
| Catalog # | MBS670331 |
| Price | $270 |
| Order / More Info | Human Caspase-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) Krumschnabel, G. et al. (2009). Cell Death and Diff. 16: 195-207.3) Tang, J. et al. (2005). Cancer Biol. Ther. 4: 645-49.4) Cohen, G.M. (1997). Biochem. J. 326: 1-16.5) Kumar, S. et al. (1994). Genes Dev. 8: 1613-26.6) Zhivotovsky, B. et al. (2005). Biochem. Biophys. Res. Commun. 331: 859-67.7) Cheung, H.H. et al. (2006). Exp. Cell. Res. 312: 2347-57.8) Droin, N.et al. (2001). Blood. 97: 1835-44.9) Prasad, V. et al. (2006). Free Radic. Biol. Med. 41: 431-42. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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