Phospho-NFKB (S536) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-NFKB (S536) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.27 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This NFKB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S536 of human NFKB. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime |
| Immunogen | n/a |
| Other Names | [Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; RELA; NFKB3] |
| Gene, Accession # | [RELA], Gene ID: 5970, NCBI: NP_001138610.1, UniProt: Q04206 |
| Catalog # | MBS9211699 |
| Price | $165, $370 |
| Order / More Info | Phospho-NFKB (S536) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zamora, M., et al., J. Biol. Chem. 279(37):38415-38423 (2004). Jeong, S.J., et al., Blood 104(5):1490-1497 (2004). Bohuslav, J., et al., J. Biol. Chem. 279(25):26115-26125 (2004). Yeh, P.Y., et al., J. Biol. Chem. 279(25):26143-26148 (2004). Jang, H.D., et al., J. Biol. Chem. 279(23):24873-24880 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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