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Antigenic Specificity | SLC18A3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Vesicular acetylcholine transporter(SLC18A3) detection. Background: The Vesicular acetylcholine transporter (VAChT), also known as SLC18A3, is a neurotransmitter transporter which is responsible for loadingacetylcholine (ACh) into secretory organelles in neurons making acetylcholine available for secretion. It is encoded by Solute carrier family 18, member 3 (SLC18A3) gene. This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline ace |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC18A3 (1-36aa MESAEPAGQARAAATKLSEAVGAALQEPRRQRRLVL), different from the related mouse and rat sequences by five amino acids. |
Other Names | [AChR; Rvat; Slc18a3; VAChT; Q16572; Vesicular acetylcholine transporter; solute carrier family 18 member A3], [SLC18A3; SLC18A3; CMS21; VACHT; VACHT; VAChT] |
Gene, Accession # | [SLC18A3], Gene ID: 6572, NCBI: NP_003046.2, UniProt: Q16572 |
Catalog # | MBS178692 |
Price | $280 |
Order / More Info | SLC18A3 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Erickson JD, Varoqui H (Dec 2000). Molecular analysis of vesicular amine transporter function and targeting to secretory organelles. FASEB Journal. 14 (15): 2450-8.2. Weihe E, Tao-Cheng JH, Schafer MK, Erickson JD, Eiden LE (Apr 1996). Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles. Proceedings of the National Academy of Sciences of the United States of America. 93 (8): 3547-52. |