Cytokeratins, basic (AE3) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cytokeratins, basic (AE3) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human, Cattle, chicken, mouse, rat, rabbit |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 mL |
| Concentration | 50 ug/ml |
| Applications | Immunohistochemistry (IHC) Formalin/Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Clone AE3 binds to most basic cytokeratins (Type II Cytokeratins pI> 6.0, high molecular weight) corresponding to Moll-nomenclature CK1, 2, 3, 4, 5, 6 and 8. Most, but not all, epithelia contain one of these cytokeratins, so that this clone will label a broad spectrum of epithelia and carcinoma. Cytokeratins are a group of water soluble filament proteins, which are components of the cyto-skeleton of the epidermis and other epithelial cells. Gel-electrophoretic investigation revealed 20 different Cytokeratins, characterised by different molecular sizes and pI-values. They can be subdivided into basic and acid subfamilies. The nomenclature according to Moll et al. (1982) is most commonly used Basic Cytokeratins (52, 56, 58, 59, 64, 65-67 kDa) |
| Immunogen | Immunogen: Human epithelial Keratins |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS397086 |
| Price | $505 |
| Order / More Info | Cytokeratins, basic (AE3) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Moll R., Franke W.W., Schiller D.L., Geiger B., and Krepler R. (1982) The Catalog of Human Cytokeratins: Patterns of Expression in Normal Epithelia, Tumors and Cultured Cells. Cell 31; 11 ff. 2. Sun T.-T. Tseng S.C.G., Huang A.J.W., Cooper D., Lynch M.H., Weiss R., Eichner R., and Schermer (1985) Monoclonal antibody studies of keratin expression: A review. In: Intermediate Filaments, Wang E. et al. eds. N.Y. Acad. Sci. 455, pp 307 ff. |
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