CD11b (N-term), 253-282 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD11b (N-term), 253-282
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.27
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB)
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DescriptionThis CD11b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human CD11b. CD11b is the integrin alpha M chain. Integrinsare heterodimeric integral membrane proteins composed of an alphachain and a beta chain. This I-domain containing alpha integrincombines with the beta 2 chain (ITGB2) to form a leukocyte-specificintegrin referred to as macrophage receptor 1 ('Mac-1'), orinactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2integrin is important in the adherence of neutrophils and monocytesto stimulated endothelium, and also in the phagocytosis ofcomplement coated particles.
Immunogenn/a
Other Names[Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; ITGAM; CD11B; CR3A]
Gene, Accession #[ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215
Catalog #MBS9213363
Price$165, $370
Order / More InfoCD11b (N-term), 253-282 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGjelstrup, L.C., et al. J. Immunol. 185(7):4154-4168(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Warchol, T., et al. DNA Cell Biol. (2010) In press : Fan, Y., et al. J Eur Acad Dermatol Venereol (2010) In press : Pliyev, B.K., et al. Biochem. Biophys. Res. Commun. 397(2):277-282(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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