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Antigenic Specificity | CD11b (N-term), 253-282 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.27 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD11b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-282 amino acids from the N-terminal region of human CD11b. CD11b is the integrin alpha M chain. Integrinsare heterodimeric integral membrane proteins composed of an alphachain and a beta chain. This I-domain containing alpha integrincombines with the beta 2 chain (ITGB2) to form a leukocyte-specificintegrin referred to as macrophage receptor 1 ('Mac-1'), orinactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2integrin is important in the adherence of neutrophils and monocytesto stimulated endothelium, and also in the phagocytosis ofcomplement coated particles. |
Immunogen | n/a |
Other Names | [Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b; ITGAM; CD11B; CR3A] |
Gene, Accession # | [ITGAM], Gene ID: 3684, NCBI: NP_000623.2, UniProt: P11215 |
Catalog # | MBS9213363 |
Price | $165, $370 |
Order / More Info | CD11b (N-term), 253-282 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gjelstrup, L.C., et al. J. Immunol. 185(7):4154-4168(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Warchol, T., et al. DNA Cell Biol. (2010) In press : Fan, Y., et al. J Eur Acad Dermatol Venereol (2010) In press : Pliyev, B.K., et al. Biochem. Biophys. Res. Commun. 397(2):277-282(2010) |