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Antigenic Specificity | Phospho-Akt2 (Ser474) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Akt2 (Ser474) antibody detects endogenous levels of Akt2 only when phosphorylated at Serine 474. Description: Akt2 an AGC kinase. Plays critical roles in glucose metabolism and the development or maintenance of proper adipose tissue and islet mass for which other Akt/PKB isoforms are unable to fully compensate.Function: AKT2 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, |
Immunogen | Immunogen: A synthesized peptide derived from human Akt2 around the phosphorylation site of Serine 474 Subcellular Location: Endosome; Nucleus; Plasma Membrane Tissue Specificity: Expressed in all cell types so far analyzed. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (91%), Bovine (100%), Horse (100%), Chicken (100%), Xenopus (100%) |
Other Names | [Akt2; AKT2_HUMAN; HIHGHH; murine thymoma viral (v-akt) homolog-2; PKB; PKB beta; PKBB; PKBBETA; PRKBB; Protein kinase Akt 2; Protein kinase Akt-2; Protein kinase B beta; rac protein kinase beta; RAC-BETA; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; v akt murine thymoma viral oncogene homolog 2] |
Gene, Accession # | [Akt2], Gene ID: 208, NCBI: NP_001317440.1, UniProt: P31751 |
Catalog # | MBS9601035 |
Price | $240, $280 |
Order / More Info | Phospho-Akt2 (Ser474) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |