CBX5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCBX5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (CHIP)
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DescriptionThe antibody detects endogenous level of total CBX5 protein. Heterochromatin protein 1 (HP1) is a family of heterochromatic adaptor molecules involved in both gene silencing and higher order chromatin structure (1). All three HP1 family members (a, b, and g) are primarily associated with centromeric heterochromatin; however, HP1b and g also localize to euchromatic sites in the genome (2,3). HP1 proteins are approximately 25 kDa in size and contain a conserved amino-terminal chromodomain, followed by a variable hinge region and a conserved carboxy-terminal chromoshadow domain. The chromodomain facilitates binding to histone H3 tri-methylated at Lys9, a histone mark closely associated with centromeric heterochromatin (4,5). The variable hin
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CBX5.
Other Names[CBX5; HP1; HP1A]
Gene, Accession #[CBX5], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973
Catalog #MBS9407458
Price$255
Order / More InfoCBX5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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