Phospho-p70 S6 Kinase beta (Ser423) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-p70 S6 Kinase beta (Ser423)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-p70 S6 Kinase beta (Ser423) antibody detects endogenous levels of p70 S6 Kinase beta only when phosphorylated at Serine 423. Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B).Function: Phosphorylates specifically ribosomal protein S6.Post-translational Modifications: Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention.Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S
ImmunogenImmunogen: A synthesized peptide derived from human p70 S6 Kinase beta around the phosphorylation site of Serine 423 Subcellular Location: Nucleus Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (91%), Bovine (91%), Horse (82%), Sheep (91%), Dog (91%)
Other Names[70 kDa ribosomal protein S6 kinase 2; EC 2.7.11.1; KS6B2_HUMAN; p70 beta; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; p70 S6Kbeta; p70(S6K) beta; p70-beta; p70-S6K 2; P70S6K2; p70S6Kb; Ribosomal protein S6 kinase 70kDa, polypeptide 2; Ribosomal protein S6 kinase beta 2; Ribosomal protein S6 kinase beta-2; Rps6kb2; S6 kinase related kinase; S6 kinase-related kinase; S6K beta 2; S6K beta; S6K-beta; S6K-beta-2; S6K2; Serine/threonine protein kinase 14 beta; Serine/threonine-protein kinase 14B; SRK; STK14B]
Gene, Accession #[RPS6KB2], Gene ID: 6199, NCBI: NP_003943.2, UniProt: Q9UBS0
Catalog #MBS9601255
Price$240, $280
Order / More InfoPhospho-p70 S6 Kinase beta (Ser423) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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