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Antigenic Specificity | MAPK10 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAPK10 |
Other Names | [mitogen-activated protein kinase 10 isoform 2; Mitogen-activated protein kinase 10; mitogen-activated protein kinase 10; mitogen-activated protein kinase 10; MAP kinase p49 3F12; Stress-activated protein kinase 1b; SAPK1b; Stress-activated protein kinase JNK3; c-Jun N-terminal kinase 3] |
Gene, Accession # | [MAPK10], Gene ID: 5602, NCBI: NP_002744.1, UniProt: P53779 |
Catalog # | MBS3220377 |
Price | $335 |
Order / More Info | MAPK10 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |