SOCS7 - N-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SOCS7 - N-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, human, mouse, porcine, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against SOCS7. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOCS7 |
| Other Names | [suppressor of cytokine signaling 7; Suppressor of cytokine signaling 7; suppressor of cytokine signaling 7; suppressor of cytokine signaling 7; Nck, Ash and phospholipase C gamma-binding protein; Nck-associated protein 4] |
| Gene, Accession # | [SOCS7], Gene ID: 30837, NCBI: NP_055413, UniProt: O14512 |
| Catalog # | MBS3211454 |
| Price | $335 |
| Order / More Info | SOCS7 - N-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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