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Antigenic Specificity | Ikaros (C-term) |
Clone | [1A12-F2-D8] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higheraffinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates theenhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent andHDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal pro |
Immunogen | Immunogen: Purified recombinant human Ikaros (C-terminus) protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of Ikaros (C-terminus) and does not cross-react with related proteins. Sequence Similarities: Belongs to the Ikaros C2H2-type zinc-finger protein family.Contains 6 C2H2-type zinc fingers. |
Other Names | [CLL associated antigen KW 6; DNA-binding protein Ikaros; hIk 1; hIk-1; Hs.54452; IK1; Ikaros (zinc finger protein); IKAROS; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; Ikzf1; IKZF1_HUMAN; LYF1; Lymphoid transcription factor LyF-1; PRO0758; Zinc finger protein subfamily 1A 1 (Ikaros); zinc finger protein subfamily 1A 1; Zinc finger protein, subfamily 1A, member 1; ZNFN1A1], [ikzf1; IK1; LYF1; hIk-1; IKAROS; PRO0758; ZNFN1A1; Hs.54452] |
Gene, Accession # | [Ikaros], Gene ID: 10320, NCBI: NP_001207694.1, UniProt: Q13422 |
Catalog # | MBS475062 |
Price | $335 |
Order / More Info | Ikaros (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |