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Antigenic Specificity | Acinus (IN) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-Acinus (IN) [Rabbit antibody to peptide corresponding to aa 775-789 of human Acinus L, and aa 17-31 of human Acinus S, and aa 48-62 of human Acinus S'. Recognizes human and mouse Acinus.]. This antibody recognizes human and mouse Acinus (220 kD). Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase-activated DNase, and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for Apoptotic Chromatin Condensation Inducer in the Nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease to generate a small active peptide, |
Immunogen | Antigen: Peptide corresponding to aa 775-789 of human AcinusL, aa 17-31 of human Acinus S and aa 48-62 of human AcinusS' which differ from those of mouse Acinus by one amino acid. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194016 |
Price | $415 |
Order / More Info | Acinus (IN) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |