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Antigenic Specificity | EHMT2 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EHMT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 361-395 amino acids from the Central region of human EHMT2. Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also mediates monomethylation of 'Lys-56' of histone H3 (H3K56me1) in G1 phase, leading to promote interaction between histone H3 and PCNA and regulating DNA replication. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required |
Immunogen | n/a |
Other Names | [Histone-lysine N-methyltransferase EHMT2; 211-; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9a; EHMT2; BAT8; C6orf30; G9A; KMT1C; NG36] |
Gene, Accession # | [EHMT2], Gene ID: 10919, NCBI: NP_001276342.1, UniProt: Q96KQ7 |
Catalog # | MBS9204155 |
Price | $165, $370 |
Order / More Info | EHMT2 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Brown S.E.,et al.Mamm. Genome 12:916-924(2001). Ota T.,et al.Nat. Genet. 36:40-45(2004). Xie T.,et al.Genome Res. 13:2621-2636(2003). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. Hirakawa M.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases. |