E-Cadherin (CDH1)/CD324 (Intercellular Junction Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityE-Cadherin (CDH1)/CD324 (Intercellular Junction Marker)
Clone[CDH1/2208R]
Host SpeciesRabbit
Reactive Specieshuman.does not react with mouse and rat.
IsotypeIgG
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionRecognizes a protein of 120-80kDa, identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- andP-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as ?-catenin, to regulate cadherin function.E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combina
ImmunogenImmunogen: Recombinant full-length human E-Cadherin protein Cellular Localization: Cell Surface
Other Names[Arc 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CD324; CDH1; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependent adhesion protein; Liver cell adhesion molecule (LCAM); Uvomorulin (UVO)]
Gene, Accession #[CDH1], Gene ID: 999, NCBI: NP_001304113.1, UniProt: P12830
Catalog #MBS4380383
Price$190, $340, $340
Order / More InfoE-Cadherin (CDH1)/CD324 (Intercellular Junction Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesUmbas, R., et al. 1992. Expression of the cellular adhesion molecule E-cadherin is reduced or absent in high-grade prostate cancer. Cancer Res. 52: 5104-5109.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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