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Antigenic Specificity | HSP70B' |
Clone | [165f] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg, 0.2 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human HSP70B'. Detects a band of ~70kDa by Western blot. The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized protei |
Immunogen | Immunogen: Synthetic peptide corresponding to the sequence near the C-terminus of human HSP70B'. |
Other Names | [HSP70B'], [HSPA6; HSPA6; HSP70B'; HSP70B'] |
Gene, Accession # | [Hsp70B prime; Heat shock protein 70 B'], Gene ID: 3310, NCBI: P17066.2, UniProt: P17066 |
Catalog # | MBS565156 |
Price | $285, $520 |
Order / More Info | HSP70B' Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |