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Antigenic Specificity | VISTA [4C4] |
Clone | [4C4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. |
Immunogen | Immunogen: VISTA antibody was raised against the extracellular domain of human VISTA. Conjugate: Unconjugated |
Other Names | [VISTA molecule; VSIR; B7-H5; B7H5; GI24; PP2135; SISP1; DD1alpha; VISTA; C10orf54; chromosome 10 open reading frame 54; PD-1H; V-set immunoregulatory receptor; V-Type Immunoglobulin Domain-Containing Suppressor Of T-Cell Activation; Chromosome 10 Open Reading Frame 54], [VSIR] |
Gene, Accession # | [VISTA], Gene ID: 64115, NCBI: NP_071436, UniProt: Q9H7M9 |
Catalog # | MBS154603 |
Price | $440 |
Order / More Info | VISTA [4C4] Antibody from MYBIOSOURCE INC. |
Product Specific References | Mayya V., et al. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. 2009, Sci. Signal. 2:RA46-RA46. Sakr M.A., et al.,GI24 enhances tumor invasiveness by regulating cell surface membrane-type 1 matrix metalloproteinase. 2010, Cancer Sci. 101:2368-2374. |