Akt2 (PKB beta) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAkt2 (PKB beta)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, bovine, chicken, dog, guinea pig, hamster, monkey, porcine, rabbit, sheep, Xenopus
Isotypen/a
FormatAPC-Cy7 conjugate
Size0.4 mL
Concentration0.25 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA (EIA)
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DescriptionDetects ~65 kDa. Does not react with PKBalpha (Akt1) or PKBgamma (Akt3). Protein kinase B or Akt (PKB/Akt) is a serine/threonine kinase, which in mammals comprises three highly homologous members known as PKB alpha (Akt1), PKB beta (Akt2) and PKB gamma (Akt3). PKB/Akt is a growth-factor-regulated protein kinase which contains a Pleckstrin Homology (PH) domain which might be important for dimerization of the kinase. Binding of phosphoinositide 3-OH kinase products to the pleckstrin homology domain results in translocation of PKB/Akt to the plasma membrane where it is activated by phosphorylation by upstream kinases including the phosphoinoside-dependent kinase 1 (PDK1) and PDK2 (1-3). Myelin basic protein and histone H2B are in vitro substra
ImmunogenImmunogen: A five residue synthetic peptide from the C-terminal of human AKT2, coupled to KLH
Other Names[Rabbit Human Akt2 (PKB beta); AKT2; PKB; PKB beta; PRKBB; protein kinase Akt2; RAC BETA]
Gene, Accession #[AKT2], Gene ID: 208, NCBI: NP_001617.1, UniProt: P31751
Catalog #MBS8004205
Price$475
Order / More InfoAkt2 (PKB beta) Antibody from MYBIOSOURCE INC.
Product Specific References1. Downward J. (1998). Curr Opin Cell Biol. 10(2): 262-7. 2. Brazil D.P., and Hemmings B.A. (2001). Biochem Sci. 26(11):657-64. 3. Nicholson K.M., Anderson N.G. (2002). Cell Signal. 14(5): 381-95. 4. Hardie, G., Hanks, S. (1995). The Protein Kinase Facts Book, Protein-Serine Kinases Academic Press Limited, San Diego, CA 418pps.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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