GRS (Glycyl-tRNA Synthetase) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GRS (Glycyl-tRNA Synthetase) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse. |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody reacts specifically with 79kDa glycyl tRNA synthetase protein. Glycyl-tRNA synthetase catalyzes the ligation of glycine with glycyl-tRNA using ATP and its mutation induces Charcot-Marie-Tooth (CMT) disease. |
| Immunogen | Immunogen: Full length native recombinant human GRS. |
| Other Names | [Glycyl-tRNA Synthetase pAb; GARS; GlyRS; DSMAV; CMT2D; SMAD1], [GARS; HMN5; CMT2D; DSMAV; GlyRS; SMAD1] |
| Gene, Accession # | [GRS], Gene ID: 2617, NCBI: BAA06338.1 |
| Catalog # | MBS490308 |
| Price | $895 |
| Order / More Info | GRS (Glycyl-tRNA Synthetase) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Secreted human glycyl-tRNA synthetase implicated in defense against ERK-activated tumorigenesis. Min Chul Park et al., PNAS, Vol.109, E640-E647, 2012. 2. Internally Deleted Human tRNA Synthetase Suggests Evolutionary Pressure for Repurposing. Zhiwen Xu et al., Structure, Vol.20, 1470-1477, 2012. 3. Aminoacyl tRNA synthetases and their connections to disease. Sang Gyu Park et al., PNAS, Vol.105(32),11043-11049, 2008. 4. Functional Analyses of Glycyl-tRNA Synthetase Mutations Suggest a Key Role for tRNA-Charging Enzymes in Peripheral Axons. Anthony Antonellis et al., The Journal of Neuroscience, Vol.26(41), 10397-10406, 2006. 5. Severe childhood SMA and axonal CMT due to anticodon binding domain mutations in the GARS gene. James P.A. et al., Neurology, Vol.67, 1710-1712, 2006. 6. Phenotypic spectrum of disorders associated with glycyl-tRNA synthetase mutations. Kumaraswamy Sivakumar et al., Brain, Vol.128, 2304-2314, 2005. 7. Glycyl tRNA synthetase mutations in Charcot-MarieTooth disease type 2D and distal spinal muscular atrophy type V. Am. Antonellis A., et al., J. Hum. Genet., Vol.72, 1293-1299, 2003. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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