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Antigenic Specificity | TRAF3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRAF3 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are the major signal transducers for the TNF receptor superfamily and the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily. TRAF3 was first identified by its interaction with CD40 and the Epstein-Barr virus transforming protein LMP1. Several TRAF3 mRNA splice variants exist and some of these can activate the transcription factor NF-κB. Besides CD40, TRAF3 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF2 and the apoptosis inhibitors cIAP1 and Smac. It has been suggested that TRAF3 induces mitochondria-mediated apoptosis upon binding of the TNF family cytokine LIGHT by LTbetaR. |
Immunogen | Immunogen: TRAF3 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TRAF3. Buffer: TRAF3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TRAF3; CAP1; LAP1; CAP-1; CRAF1; IIAE5; CD40bp; CAP1; TNF receptor-associated factor 3; TNF receptor-associated factor 3], [TRAF3; TRAF3; CAP1; LAP1; CAP-1; CRAF1; IIAE5; CD40bp; CAP1; CRAF1; CRAF1; CD40BP; LAP1] |
Gene, Accession # | [TRAF3], Gene ID: 7187, NCBI: NP_663777, UniProt: Q13114 |
Catalog # | MBS151227 |
Price | $375 |
Order / More Info | TRAF3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |