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Antigenic Specificity | Polycomb complex protein BMI-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Polycomb complex protein BMI-1 polyclonal antibody. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. |
Immunogen | Immunogen: Recombinant Human Polycomb complex protein BMI-1 protein |
Other Names | [Polycomb group RING finger protein 4; RING finger protein 51] |
Gene, Accession # | Gene ID: 100532731, NCBI: NP_001190991.1, UniProt: P35226 |
Catalog # | MBS9415924 |
Price | $320 |
Order / More Info | Polycomb complex protein BMI-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |