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Antigenic Specificity | Mouse Lysyl oxidase homolog 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of |
Immunogen | Immunogen: Recombinant mouse Lysyl oxidase homolog 2 protein(26-776aa) |
Other Names | [Lysyl oxidase-like protein 2; Loxl2], [Loxl2; Loxl2; 1110004B06Rik; 4930526G11Rik; 9430067E15Rik] |
Gene, Accession # | Gene ID: 94352, NCBI: NP_201582.2, UniProt: P58022 |
Catalog # | MBS1494129 |
Price | $160, $235 |
Order / More Info | Mouse Lysyl oxidase homolog 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |