Mouse Lysyl oxidase homolog 2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse Lysyl oxidase homolog 2
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionMediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated Lys-4 of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of
ImmunogenImmunogen: Recombinant mouse Lysyl oxidase homolog 2 protein(26-776aa)
Other Names[Lysyl oxidase-like protein 2; Loxl2], [Loxl2; Loxl2; 1110004B06Rik; 4930526G11Rik; 9430067E15Rik]
Gene, Accession #Gene ID: 94352, NCBI: NP_201582.2, UniProt: P58022
Catalog #MBS1494129
Price$160, $235
Order / More InfoMouse Lysyl oxidase homolog 2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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