Description | Specificity: Myc-tag Monoclonal Antibody. Recognises over-expressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins in transfected mammalian cells. This gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG sta |
Product Specific References | Ahn, CS et al. Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway. J. Exp. Bot. : (2014). PubMed: 25399018.Su,, B. et al. A Genome-Wide RNAi Screen Identifies FOXO4 as a Metastasis-Suppressor through Counteracting PI3K/AKT Signal Pathway in Prostate Cancer. Plos One 9 (7): (2014). PubMed: 24983969.Shi, XH et al. The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts. PLoS One 8 (9):e75473 (2013). DOI: 10.1371/journal.pone.0075473. Application: Western Blot.Shi, XH et al. The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts. PLoS ONE 8:e75473 (2013). PubMed: 24066183.Zhang, A et al. The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage. Cell Res. 23(3):340-50 (2013). DOI: 10.1038/cr.2012.164. PubMed: 23208419.Kim, JH et al. The Arabidopsis RING E3 ubiquitin ligase AtAIRP3, LOG2 participates in positive regulation of high-salt and drought stress responses. Plant Physiol 162:1733-49 (2013). PubMed: 23696092.Petzold, CJ et al. Cells determine cell density using a small protein bound to a unique tissue-specific phospholipid. PeerJ 1:e192 (2013). PubMed: 24244914.Tattoli, I et al. Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program. Cell Host Microbe 11 (6):563-575 (2012). DOI: 10.1016/j.chom.2012.04.012. Application: Western Blot.Sachdeva, M et al. Negative regulation of miR-145 by C/EBP-beta through the Akt pathway in cancer cells. Nucleic Acids Res 40(14):6683-92 (2012). DOI: 10.1093/nar/gks324. PubMed: 22495929.Schmid, D et al. An abundant, truncated human sulfonylurea receptor 1 splice variant has prodiabetic properties and impairs sulfonylurea action. Cell Mol Life Sci 69:129-48 (2012). PubMed: 21671119.Liu, TT et al. Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23:2505-15 (2012). PubMed: 22593205.Rothenburg, S et al. Characterization of a ranavirus inhibitor of the antiviral protein kinase PKR. BMC Microbiol 11:56 (2011). DOI: 10.1186/1471-2180-11-56. Application: Western Blot.Jung, H et al. Mest, Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation. Biochem. J. 436:263-9 (2011). PubMed: 21375506. Application: Immunoprecipitation.Christova, T et al. Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription. Int J Biochem & Cell Biol 42 (5):630-640 (2010). DOI: 10.1007/978-1-61779-455-1_15. Application: Western Blot.Mo, Y.Y et al. MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1. Journal of Cancer Res 70 (1):278-287 (2010). DOI: 10.1158/0008-5472. Application: Western Blot.Son, O et al. In vitro and in vivo interaction of AtRma2 E3 ubiquitin ligase and auxin binding protein 1. Biochem Biophys Res Commun 396 (3):492-497 (2010). DOI: 10.1016/j.bbrc.2010.02.032. PubMed: 20152813. Application: Immunoblot.Sachdeva, M et al. MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res 70(1):378-87 (2010). DOI: 10.1158/0008-5472.CAN-09-2021. PubMed: 19996288.McPherson, VA et al. Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol 29 (2):389-401 (2008). DOI: 10.1128/MCB.00904-08. Application: Immunostaining.Cho, SK et al. Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress. Plant Cell 20:1899-914 (2008). PubMed: 18664614.Zhu, S et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18:350-9 (2008). PubMed: 18270520.Wu, F et al. Gam1-associated alterations of drug responsiveness through activation of apoptosis. Mol Cancer Ther 6 (6):1823-1830 (2007). PubMed: 17575111. Application: Western Blot.Mller, I et al. Ca2 signaling and gene transcription in glucose-stimulated insulinoma cells. Cell Calcium 52 (2):137-51 (2012). PubMed: 22658828. Application: Immunoblot. |