Myc Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMyc
Clonemonoclonal
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
Formatunconjugated
Size0.1 mg, 1 mg
Concentration100ug/100ul
ApplicationsImmunofluorescence (IF), ELISA (EIA), Dot Blot (DB), Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
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DescriptionSpecificity: Myc-tag Monoclonal Antibody. Recognises over-expressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins in transfected mammalian cells. This gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG sta
ImmunogenImmunogen: A synthetic peptide corresponding to residues 410-419 (EQKLISEEDL) coupled to KLH.
Other Namesn/a
Gene, Accession #[Myc], NCBI: NP_955602.1
Catalog #MBS415332
Price$230, $1260
Order / More InfoMyc Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAhn, CS et al. Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway. J. Exp. Bot. : (2014). PubMed: 25399018.Su,, B. et al. A Genome-Wide RNAi Screen Identifies FOXO4 as a Metastasis-Suppressor through Counteracting PI3K/AKT Signal Pathway in Prostate Cancer. Plos One 9 (7): (2014). PubMed: 24983969.Shi, XH et al. The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts. PLoS One 8 (9):e75473 (2013). DOI: 10.1371/journal.pone.0075473. Application: Western Blot.Shi, XH et al. The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts. PLoS ONE 8:e75473 (2013). PubMed: 24066183.Zhang, A et al. The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage. Cell Res. 23(3):340-50 (2013). DOI: 10.1038/cr.2012.164. PubMed: 23208419.Kim, JH et al. The Arabidopsis RING E3 ubiquitin ligase AtAIRP3, LOG2 participates in positive regulation of high-salt and drought stress responses. Plant Physiol 162:1733-49 (2013). PubMed: 23696092.Petzold, CJ et al. Cells determine cell density using a small protein bound to a unique tissue-specific phospholipid. PeerJ 1:e192 (2013). PubMed: 24244914.Tattoli, I et al. Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program. Cell Host Microbe 11 (6):563-575 (2012). DOI: 10.1016/j.chom.2012.04.012. Application: Western Blot.Sachdeva, M et al. Negative regulation of miR-145 by C/EBP-beta through the Akt pathway in cancer cells. Nucleic Acids Res 40(14):6683-92 (2012). DOI: 10.1093/nar/gks324. PubMed: 22495929.Schmid, D et al. An abundant, truncated human sulfonylurea receptor 1 splice variant has prodiabetic properties and impairs sulfonylurea action. Cell Mol Life Sci 69:129-48 (2012). PubMed: 21671119.Liu, TT et al. Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23:2505-15 (2012). PubMed: 22593205.Rothenburg, S et al. Characterization of a ranavirus inhibitor of the antiviral protein kinase PKR. BMC Microbiol 11:56 (2011). DOI: 10.1186/1471-2180-11-56. Application: Western Blot.Jung, H et al. Mest, Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation. Biochem. J. 436:263-9 (2011). PubMed: 21375506. Application: Immunoprecipitation.Christova, T et al. Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription. Int J Biochem & Cell Biol 42 (5):630-640 (2010). DOI: 10.1007/978-1-61779-455-1_15. Application: Western Blot.Mo, Y.Y et al. MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1. Journal of Cancer Res 70 (1):278-287 (2010). DOI: 10.1158/0008-5472. Application: Western Blot.Son, O et al. In vitro and in vivo interaction of AtRma2 E3 ubiquitin ligase and auxin binding protein 1. Biochem Biophys Res Commun 396 (3):492-497 (2010). DOI: 10.1016/j.bbrc.2010.02.032. PubMed: 20152813. Application: Immunoblot.Sachdeva, M et al. MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res 70(1):378-87 (2010). DOI: 10.1158/0008-5472.CAN-09-2021. PubMed: 19996288.McPherson, VA et al. Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol 29 (2):389-401 (2008). DOI: 10.1128/MCB.00904-08. Application: Immunostaining.Cho, SK et al. Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress. Plant Cell 20:1899-914 (2008). PubMed: 18664614.Zhu, S et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 18:350-9 (2008). PubMed: 18270520.Wu, F et al. Gam1-associated alterations of drug responsiveness through activation of apoptosis. Mol Cancer Ther 6 (6):1823-1830 (2007). PubMed: 17575111. Application: Western Blot.Mller, I et al. Ca2 signaling and gene transcription in glucose-stimulated insulinoma cells. Cell Calcium 52 (2):137-51 (2012). PubMed: 22658828. Application: Immunoblot.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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