Edit |   |
---|---|
Antigenic Specificity | Cathepsin B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form. Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy suggesting that this enzyme may be a useful prognostic marker for several types of human cancers. |
Immunogen | Immunogen: Cathepsin B antibody was raised in Rabbit using synthetic peptide surrounding amino acid 322 of human cathepsins B as the immunogen. |
Other Names | [Rabbit Cathepsin B; Cathepsin B; Cathepsin B; EC 3.4.22.1; CTSB; CPSB; APPS] |
Gene, Accession # | [CPSB], Gene ID: 1508, UniProt: P07858 |
Catalog # | MBS5311211 |
Price | $465 |
Order / More Info | Cathepsin B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |